Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | AURKA | O14965 | 2/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.52 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14901035 | 0.80 | RAB9A (0.66) | MAPK8RAB9ANPC1HPGDMAPT | |
| SCHEMBL14441238 | 0.78 | HCAR2 (0.62) | RAB9ANPC1KDM4ETSHRALDH1A1 | |
| SCHEMBL7391673 | 0.78 | NPC1 (0.52) | MAPK8RAB9ANPC1HPGDMAPT | |
| SCHEMBL179015 | 0.77 | RAB9A (0.71) | MAPK8RAB9ANPC1MAPTKMT2A | |
| SCHEMBL18047119 | 0.77 | HDAC1 (0.53) | MAPK8RAB9ANPC1PARP14HPGD | |
| SCHEMBL18047116 | 0.77 | HDAC1 (0.53) | MAPK8RAB9ANPC1PARP14HPGD | |
| SCHEMBL1272814 | 0.77 | ALDH1A1 (0.62) | MAPK8RAB9ANPC1HPGDCYP1A2 | |
| SCHEMBL3628197 | 0.76 | SIRT2 (0.70) | MAPK8HPGDMAPTKMT2AKDM4E | |
| SCHEMBL14441240 | 0.76 | HCAR2 (0.61) | RAB9ANPC1MAPTKMT2AKDM4E | |
| SCHEMBL8639777 | 0.75 | RAB9A (0.67) | RAB9ANPC1HPGDMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855387-A1 | 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |