Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.37 |
| ▸ | MPEG1 | Q2M385 | 7/20 | 0.37 |
| ▸ | XIAP | P98170 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640870 | 1.00 | ACHE (0.37) | ACHEBACE1GPR84ALOX5MPEG1 | |
| SCHEMBL9360177 | 1.00 | ACHE (0.37) | ACHEBACE1GPR84ALOX5MPEG1 | |
| SCHEMBL8638891 | 0.98 | ACHE (0.34) | ACHEBACE1GPR84ALOX5MPEG1 | |
| SCHEMBL11238526 | 0.81 | ACHE (0.35) | ACHEBACE1GPR84ALOX5MPEG1 | |
| SCHEMBL1754051 | 0.80 | TSHR (0.42) | ACHEKDM4EALDH1A1TP53HSD17B10 | |
| SCHEMBL6751772 | 0.80 | TSHR (0.42) | ACHEKDM4EALDH1A1TP53HSD17B10 | |
| SCHEMBL6752031 | 0.80 | TSHR (0.42) | ACHEKDM4EALDH1A1TP53HSD17B10 | |
| SCHEMBL6750456 | 0.80 | TSHR (0.42) | ACHEKDM4EALDH1A1TP53HSD17B10 | |
| SCHEMBL6748375 | 0.80 | TSHR (0.42) | ACHEKDM4EALDH1A1TP53HSD17B10 | |
| SCHEMBL1753858 | 0.80 | TSHR (0.42) | ACHEKDM4EALDH1A1TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571652-B1 | Liquid crystalline substituted dihydrobenzene derivatives | CITIZEN WATCH CO LTD (JP) | 1998-08-05 | — | — | EP | disclosed |
| US-5342546-A | Liquid crystal compositions | L.C.C. CONSULTANTS CO., LTD. (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0571652-A1 | Liquid crystalline substituted dihydrobenzene derivatives | L.C.C. CONSULTANTS CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |