Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6748326 | 1.00 | TSHR (0.42) | TSHRTHRBPTGS2ESR1ADRA2A | |
| SCHEMBL6750444 | 1.00 | TSHR (0.42) | TSHRTHRBPTGS2ESR1ADRA2A | |
| SCHEMBL6750456 | 1.00 | TSHR (0.42) | TSHRTHRBPTGS2ESR1ADRA2A | |
| SCHEMBL6748300 | 1.00 | TSHR (0.42) | TSHRTHRBPTGS2ESR1ADRA2A | |
| SCHEMBL6751772 | 1.00 | TSHR (0.42) | TSHRTHRBPTGS2ESR1ADRA2A | |
| SCHEMBL1753858 | 1.00 | TSHR (0.42) | TSHRTHRBPTGS2ESR1ADRA2A | |
| SCHEMBL1754051 | 1.00 | TSHR (0.42) | TSHRTHRBPTGS2ESR1ADRA2A | |
| SCHEMBL6752031 | 1.00 | TSHR (0.42) | TSHRTHRBPTGS2ESR1ADRA2A | |
| SCHEMBL1754426 | 0.97 | — | — | |
| Diethylamine SCHEMBL6750381 | 0.89 | TSHR (0.36) | TSHRTHRBPTGS2ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233669-B1 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | UNIV NORTH CAROLINA STATE (US) | 2004-02-25 | — | — | EP | claimed |
| EP-1233669-A2 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-08-28 | — | — | EP | claimed |
| US-6365549-B2 | PRESERVATION | NORTH CAROLINA STATE UNIVERSITY | 2002-04-02 | — | — | US | claimed |
| US-20010019995-A1 | Methods of blocking an ethylene response in plants using cyclopropene derivatives | NORTH CAROLINA STATE UNIVERSITY | 2001-09-06 | — | — | US | claimed |
| WO-2001037663-A2 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2001-05-31 | — | — | WO | claimed |
| EP-0376042-B1 | Improved chemical process for preparing antibiotic L 17392 (deglucoteicoplanin) and its salts | LEPETIT SPA (IT) | 1996-03-13 | — | — | EP | claimed |
| CN-108410258-B | Sun-proof gravure printing ink | 湖北中烟工业有限责任公司 | 2021-08-27 | — | — | CN | disclosed |
| CN-112174858-A | Beta-naphthalenesulfonic acid and refining method, filtrate and application thereof | 安徽生源化工有限公司 | 2021-01-05 | — | — | CN | disclosed |
| US-9072293-B2 | Cyclopropenes and method for applying cyclopropenes to agricultural products or crops | ERUM BIOTECHNOLOGIES INC. (KR) | 2015-07-07 | — | — | US | disclosed |
| CN-102843906-B | Cyclopropene compounds and methods of adding the compounds to agricultural crops | ERUM BIOTECHNOLOGIES INC | 2015-07-01 | — | — | CN | disclosed |
| EP-2561754-A2 | CYCLOPROPENE COMPOUND, AND METHOD FOR ADDING SAME TO CROPS | Erum Biotechnologies Inc. (KR) | 2013-02-27 | — | — | EP | disclosed |
| CN-102843906-A | Cyclopropene compounds and methods of adding the compounds to agricultural crops | ERUM BIOTECHNOLOGIES INC | 2012-12-26 | — | — | CN | disclosed |
| US-20120322662-A1 | CYCLOPROPENES AND METHOD FOR APPLYING CYCLOPROPENES TO AGRICULTURAL PRODUCTS OR CROPS | ERUM BIOTECHNOLOGIES INC. (KR) | 2012-12-20 | — | — | US | disclosed |
| EP-0381149-B1 | Optically active compound, liquid crystal composition and liquid crystal device comprising same | SHARP KK (JP) | 1996-03-27 | — | — | EP | disclosed |
| EP-0381149-A2 | Optically active compound, liquid crystal composition and liquid crystal device comprising same | SHARP KABUSHIKI KAISHA (JP) | 1990-08-08 | — | — | EP | disclosed |
| US-4297284-A | BY THE CYCLIZATION OF ISOBUTENYL-PYROCATECHOL OR A MIXTURE WITH METHALLYLPYROCATECHOL USING A SULFONIC ACID CATALYST | RHONE-POULENC AGROCHIMIE (FR) | 1981-10-27 | — | — | US | disclosed |
| US-4159267-A | Novel silyl ester azetidine-2-sulfenate intermediates and process for preparing desacetoxycephalosporins | ELI LILLY AND COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010019995-A1 | Methods of blocking an ethylene response in plants using cyclopropene derivatives | PRUNE1, NOTUM, FAR1 | TSHR 2454/4885THRB 1839/4885PTGS2 204/4885 |
| US-20120322662-A1 | CYCLOPROPENES AND METHOD FOR APPLYING CYCLOPROPENES TO AGRICULTURAL PRODUCTS OR CROPS | GLA, PFAS, AMY1A | TSHR 1706/4885THRB 3693/4885PTGS2 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.