Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27409995 | 0.83 | KDM4E (0.55) | KDM4EPKMGPR119MEN1KMT2A | |
| SCHEMBL8630074 | 0.82 | MAPT (0.39) | PKMLMNA | |
| SCHEMBL8630070 | 0.82 | MAPT (0.39) | PKMLMNA | |
| SCHEMBL18891231 | 0.81 | KDM4E (0.64) | KDM4EPKMGPR119MEN1KMT2A | |
| SCHEMBL8841108 | 0.79 | KDM4E (0.61) | KDM4EPKMGPR119MEN1KMT2A | |
| SCHEMBL4209884 | 0.78 | KDM4E (0.65) | KDM4EPKMGPR119MEN1KMT2A | |
| SCHEMBL8629722 | 0.77 | BCHE (0.49) | KDM4EKMT2A | |
| SCHEMBL8629719 | 0.77 | BCHE (0.49) | KDM4EKMT2A | |
| SCHEMBL8427792 | 0.77 | GPR119 (0.60) | KDM4EPKMGPR119MEN1KMT2A | |
| SCHEMBL22633427 | 0.77 | KDM4E (0.61) | KDM4EPKMGPR119MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |