SCHEMBL8636717

SCHEMBL8636717

CCCC1C=CC(c2ccc(F)cc2)=CC1

nearest known ligand 0.30

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30
KMT2A Q03164 1/20 0.30
KDM1A O60341 1/20 0.30
RCOR1 Q9UKL0 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8638145 0.91 PSMD14 (0.31)
SCHEMBL8636477 0.90 GRM2 (0.35)
SCHEMBL8637039 0.88 GRM2 (0.37) GAA
SCHEMBL8640995 0.88 GRM2 (0.37) GAA
SCHEMBL8637984 0.88 GRM2 (0.37) GAA
SCHEMBL8640877 0.88 GRM2 (0.37) GAA
SCHEMBL8636705 0.88 GRM2 (0.37) GAA
SCHEMBL8641227 0.87 KDM1A (0.32) KDM1ARCOR1
SCHEMBL8638340 0.86 ROCK1 (0.30)
SCHEMBL8639829 0.84 KDM1A (0.30) KDM1ARCOR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0571652-B1 Liquid crystalline substituted dihydrobenzene derivatives CITIZEN WATCH CO LTD (JP) 1998-08-05 EP disclosed
US-5342546-A Liquid crystal compositions L.C.C. CONSULTANTS CO., LTD. (JP) 1994-08-30 US disclosed
EP-0571652-A1 Liquid crystalline substituted dihydrobenzene derivatives L.C.C. CONSULTANTS CO., LTD. (JP) 1993-12-01 EP disclosed