Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791382 | 0.81 | KCNN4 (0.50) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL30501769 | 0.81 | KCNN4 (0.50) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL8591922 | 0.80 | KCNN4 (0.49) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL29009855 | 0.80 | KCNN4 (0.49) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL6400375 | 0.80 | KCNN4 (0.49) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL6229462 | 0.79 | KCNN4 (0.51) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL8637486 | 0.78 | MAPT (0.42) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| Hydrochloric Acid SCHEMBL3621250 | 0.77 | KCNN4 (0.50) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL25421703 | 0.76 | KCNN4 (0.45) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL30628289 | 0.76 | KCNN4 (0.51) | KCNN4HDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577712-B1 | FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES | DU PONT (US) | 1998-07-29 | — | — | EP | disclosed |
| EP-0577712-A1 | FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-01-12 | — | — | EP | disclosed |
| WO-1992016515-A1 | FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-01 | — | — | WO | disclosed |
| EP-0503798-A1 | Fungicidal 4-thixooxazolidin-2-ones and 4-iminooxazolindin-2-ones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-16 | — | — | EP | disclosed |