Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8591922 | 1.00 | KCNN4 (0.49) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL405869 | 0.87 | KCNN4 (0.46) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL8636719 | 0.84 | KCNN4 (0.44) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL2791382 | 0.83 | KCNN4 (0.50) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL30501769 | 0.83 | KCNN4 (0.50) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL29009855 | 0.81 | KCNN4 (0.49) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL8636724 | 0.81 | KCNN4 (0.41) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL3169297 | 0.81 | KCNN4 (0.51) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL8780648 | 0.81 | HDAC6 (0.43) | KCNN4HDAC3HDAC1HDAC2HDAC6 | |
| Bromomethane SCHEMBL3179019 | 0.80 | KCNN4 (0.47) | KCNN4HDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846835-B2 | Treating chronic obstructive pulmonary disease, chronic bronchitis, asthma, chronic respiratory tract obstruction, fibroid lung, pulmonary emphysema or rhinitis | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-01-25 | — | — | US | disclosed |
| US-20030191316-A1 | Ester derivatives | MSD K.K. (JP) | 2003-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191316-A1 | Ester derivatives | CHRM3, CHRM2, CHRM1 | KCNN4 297/4885HDAC3 530/4885HDAC1 1731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.