Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17157482 | 0.82 | MAPT (0.45) | MAPTRAB9APOLBFBP1TSHR | |
| SCHEMBL30628314 | 0.82 | MAPT (0.45) | MAPTRAB9APOLBFBP1TSHR | |
| SCHEMBL8636721 | 0.78 | KCNN4 (0.47) | RAB9AHTTNPC1ALDH1A1KCNN4 | |
| Hydrochloric Acid SCHEMBL1420789 | 0.76 | MAPT (0.40) | MAPTRAB9APOLBTSHRNPC1 | |
| Hydrochloric Acid SCHEMBL1420793 | 0.76 | MAPT (0.40) | MAPTRAB9APOLBTSHRNPC1 | |
| SCHEMBL8871152 | 0.76 | CYP3A4 (0.40) | MAPTRAB9APOLBFBP1TSHR | |
| SCHEMBL25303983 | 0.76 | FBP1 (0.43) | MAPTRAB9APOLBFBP1TSHR | |
| SCHEMBL31294683 | 0.75 | MAPT (0.41) | MAPTRAB9APOLBFBP1TSHR | |
| SCHEMBL9363344 | 0.75 | MAPT (0.41) | MAPTRAB9APOLBFBP1TSHR | |
| SCHEMBL8873708 | 0.74 | CYP3A4 (0.40) | MAPTRAB9APOLBFBP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577712-B1 | FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES | DU PONT (US) | 1998-07-29 | — | — | EP | disclosed |
| EP-0503798-A1 | Fungicidal 4-thixooxazolidin-2-ones and 4-iminooxazolindin-2-ones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-16 | — | — | EP | disclosed |