Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | SLC9A3 | P48764 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635603 | 0.90 | KDM1A (0.44) | SLC9A3EPHX2KDM1AMAOBCKS1B | |
| SCHEMBL7375058 | 0.90 | KDM1A (0.46) | CYP2D6SLC9A3EPHX2KDM1AMAOB | |
| SCHEMBL8635984 | 0.90 | KDM1A (0.46) | CYP2D6SLC9A3EPHX2KDM1AMAOB | |
| SCHEMBL7375062 | 0.90 | KDM1A (0.46) | CYP2D6SLC9A3EPHX2KDM1AMAOB | |
| SCHEMBL8633998 | 0.86 | KDM1A (0.44) | CYP2D6SLC9A3EPHX2KDM1AMAOB | |
| SCHEMBL8637606 | 0.81 | SLC6A2 (0.44) | CYP2D6SLC9A3TRPV1EPHX2KDM1A | |
| SCHEMBL8635440 | 0.81 | KMT2A (0.43) | SLC9A3EPHX2KDM1AMAOB | |
| SCHEMBL8635445 | 0.81 | KMT2A (0.43) | SLC9A3EPHX2KDM1AMAOB | |
| SCHEMBL8635442 | 0.81 | KMT2A (0.43) | SLC9A3EPHX2KDM1AMAOB | |
| SCHEMBL7372271 | 0.81 | SLC9A3 (0.41) | CYP2D6SLC9A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773463-A | DECALCIFICATION OF BRAIN DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-06-30 | — | — | US | disclosed |