SCHEMBL8636829

SCHEMBL8636829

CC(C)c1ccc(Oc2cccc(C(C)C)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.54
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
ALDH1A1 P00352 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
MAPT P10636 2/20 0.50
MITF O75030 1/20 0.50
GAA P10253 1/20 0.50
GFER P55789 1/20 0.50
NLRP1 Q9C000 1/20 0.50
NOD2 Q9HC29 1/20 0.50
CYP2D6 P10635 1/20 0.49
HPGD P15428 1/20 0.47
ALOX5 P09917 1/20 0.46
KDM4E B2RXH2 1/20 0.46
TSHR P16473 1/20 0.46
ACACB O00763 2/20 0.44
ACACA Q13085 1/20 0.44
HDAC4 P56524 1/20 0.42
HDAC8 Q9BY41 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL123764 0.96 PTGS1 (0.58) PTGS1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL30345552 0.92 PTGS1 (0.56) PTGS1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL11063307 0.92 PTGS1 (0.56) PTGS1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL14020500 0.91 PTGS1 (0.50) PTGS1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL30358257 0.90 PTGS1 (0.66) PTGS1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL765113 0.90 PTGS1 (0.66) PTGS1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL15849013 0.90 PTGS1 (0.55) PTGS1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL257802 0.89 ALDH1A1 (0.53) PTGS1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL14020499 0.89 SMN1; SMN2 (0.58) PTGS1MEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL19807299 0.87 PTGS1 (0.50) PTGS1MEN1KMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9209403-B2 Method for fabricating flexible electrical devices INDUSTRIAL TECHNOLOGY RESEARCH CENTER (TW) 2015-12-08 US disclosed
US-8859715-B2 Polyimide polymer solution, polyimide polymer, transparent film, displaying device and solar cell INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2014-10-14 US disclosed
US-20130267061-A1 METHOD FOR FABRICATING FLEXIBLE ELECTRICAL DEVICES INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2013-10-10 US disclosed
US-8420686-B2 Linked diimidazole antivirals ENANTA PHARMACEUTICALS, INC. (US) 2013-04-16 US disclosed
US-20120160317-A1 POLYIMIDE POLYMER SOLUTION, POLYIMIDE POLYMER, TRANSPARENT FILM, DISPLAYING DEVICE AND SOLAR CELL INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2012-06-28 US disclosed
US-20120160317-A1 POLYIMIDE POLYMER SOLUTION, POLYIMIDE POLYMER, TRANSPARENT FILM, DISPLAYING DEVICE AND SOLAR CELL INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2012-06-28 US disclosed
US-20110155235-A1 POLYIMIDE POLYMERS FOR FLEXIBLE ELECTRICAL DEVICE SUBSTRATE MATERIALS AND FLEXIBLE ELECTRICAL DEVICES COMPRISING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2011-06-30 US disclosed
US-20110155235-A1 POLYIMIDE POLYMERS FOR FLEXIBLE ELECTRICAL DEVICE SUBSTRATE MATERIALS AND FLEXIBLE ELECTRICAL DEVICES COMPRISING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2011-06-30 US disclosed
US-20100226882-A1 LINKED DIIMIDAZOLE ANTIVIRALS ENANTA PHARMACEUTICALS, INC. 2010-09-09 US disclosed
EP-0504541-B1 Improved catalytic process for selective alkylation of aromatic hydrocarbons SOLUTIA EUROP NV SA (BE) 1998-07-22 EP disclosed
US-5233111-A CATALYTIC PROCESS FOR SELECTIVE ALKYLATION OF AROMATIC HYDROCARBONS MONSANTO COMPANY (US) 1993-08-03 US disclosed
EP-0504541-A1 Improved catalytic process for selective alkylation of aromatic hydrocarbons MONSANTO EUROPE S.A./N.V. (BE) 1992-09-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100226882-A1 LINKED DIIMIDAZOLE ANTIVIRALS EIF2AK2, ZC3HAV1, MAVS PTGS1 1416/4885MEN1 4813/4885KMT2A 2840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.