Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637520 | 0.96 | TLR8 (0.36) | TLR8CYP1A2CYP3A4TSHRCYP2C19 | |
| SCHEMBL8640019 | 0.95 | TLR8 (0.35) | TLR8CYP1A2CYP3A4TSHRCYP2C19 | |
| SCHEMBL8643219 | 0.95 | TLR8 (0.35) | TLR8CYP1A2CYP3A4TSHRCYP2C19 | |
| SCHEMBL8639780 | 0.95 | TLR8 (0.35) | TLR8CYP1A2CYP3A4TSHRCYP2C19 | |
| SCHEMBL8641182 | 0.95 | TLR8 (0.35) | TLR8CYP1A2CYP3A4TSHRCYP2C19 | |
| SCHEMBL8640842 | 0.95 | TLR8 (0.35) | TLR8CYP1A2CYP3A4TSHRCYP2C19 | |
| SCHEMBL8639440 | 0.92 | KDM1A (0.35) | KDM1ARCOR1HTTKIF11DRD2 | |
| SCHEMBL8641186 | 0.86 | KDM1A (0.36) | KDM1ARCOR1HTTLMNASMN1; SMN2 | |
| SCHEMBL8638145 | 0.85 | PSMD14 (0.31) | TLR8 | |
| SCHEMBL8638434 | 0.82 | NPC1 (0.33) | CYP3A4TSHRCYP2C19CYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571652-B1 | Liquid crystalline substituted dihydrobenzene derivatives | CITIZEN WATCH CO LTD (JP) | 1998-08-05 | — | — | EP | disclosed |
| US-5342546-A | Liquid crystal compositions | L.C.C. CONSULTANTS CO., LTD. (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0571652-A1 | Liquid crystalline substituted dihydrobenzene derivatives | L.C.C. CONSULTANTS CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |