Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 6/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | HEXA | P06865 | 1/20 | 0.31 |
| ▸ | HEXB | P07686 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637216 | 0.92 | TLR8 (0.34) | KDM1ARCOR1KIF11HTTDRD2 | |
| SCHEMBL8637520 | 0.91 | TLR8 (0.36) | KDM1ARCOR1KIF11HTTDRD2 | |
| SCHEMBL8640019 | 0.89 | TLR8 (0.35) | KDM1ARCOR1KIF11HTTDRD2 | |
| SCHEMBL8640842 | 0.89 | TLR8 (0.35) | KDM1ARCOR1KIF11HTTDRD2 | |
| SCHEMBL8643219 | 0.89 | TLR8 (0.35) | KDM1ARCOR1KIF11HTTDRD2 | |
| SCHEMBL8639780 | 0.89 | TLR8 (0.35) | KDM1ARCOR1KIF11HTTDRD2 | |
| SCHEMBL8641182 | 0.89 | TLR8 (0.35) | KDM1ARCOR1KIF11HTTDRD2 | |
| SCHEMBL8641186 | 0.88 | KDM1A (0.36) | KDM1ARCOR1KIF11HTTCHKA | |
| SCHEMBL8636717 | 0.84 | ALDH1A1 (0.30) | KDM1ARCOR1 | |
| SCHEMBL8638340 | 0.82 | ROCK1 (0.30) | ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571652-B1 | Liquid crystalline substituted dihydrobenzene derivatives | CITIZEN WATCH CO LTD (JP) | 1998-08-05 | — | — | EP | disclosed |
| US-5342546-A | Liquid crystal compositions | L.C.C. CONSULTANTS CO., LTD. (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0571652-A1 | Liquid crystalline substituted dihydrobenzene derivatives | L.C.C. CONSULTANTS CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |