SCHEMBL8637362

SCHEMBL8637362

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nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 2/20 0.35
GABRP O00591 2/20 0.33
GABRD O14764 2/20 0.33
GABRA1 P14867 2/20 0.33
GABRB1 P18505 2/20 0.33
GABRG2 P18507 2/20 0.33
GABRB3 P28472 2/20 0.33
GABRA5 P31644 2/20 0.33
GABRA3 P34903 2/20 0.33
GABRA2 P47869 2/20 0.33
GABRB2 P47870 2/20 0.33
GABRA4 P48169 2/20 0.33
GABRE P78334 2/20 0.33
GABRA6 Q16445 2/20 0.33
GABRG1 Q8N1C3 2/20 0.33
GABRG3 Q99928 2/20 0.33
GABRQ Q9UN88 2/20 0.33
GRIN2D O15399 2/20 0.33
GRIN3B O60391 2/20 0.33
GRIN1 Q05586 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1988217 1.00 SLC1A1 (0.35) SLC1A1GABRPGABRDGABRA1GABRB1
Serine SCHEMBL21569404 0.89 SLC1A1 (0.39) SLC1A1GABRPGABRDGABRA1GABRB1
SCHEMBL9236585 0.87 LTA4H (0.35) SLC1A1GABRPGABRDGABRA1GABRB1
SCHEMBL1444867 0.87 SLC1A1 (0.50) SLC1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL30859659 0.87 LTA4H (0.35) SLC1A1GABRPGABRDGABRA1GABRB1
SCHEMBL29291859 0.85 SLC1A1 (0.42) SLC1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL1537429 0.85 SLC7A5 (0.44) SLC1A1GABRPGABRDGABRA1GABRB1
SCHEMBL1529903 0.85 SLC7A5 (0.34) SLC1A1GABRPGABRDGABRA1GABRB1
SCHEMBL3402553 0.85 GABRP (0.52) SLC1A1GABRPGABRDGABRA1GABRB1
SCHEMBL432399 0.85 PMP22 (0.50) SLC1A1GABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0856059-A1 METHODS FOR PRODUCTION OF RECOMBINANT PLASMIDS BIOSTAR INC. (CA) 1998-08-05 EP disclosed
WO-1997014805-A2 METHODS FOR PRODUCTION OF RECOMBINANT PLASMIDS BIOSTAR, INC. (CA) 1997-04-24 WO disclosed