Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.42 |
| ▸ | TUBB | P07437 | 3/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634790 | 0.91 | MAPT (0.48) | MAPTHPGDKDM4EMEN1CYP1A2 | |
| SCHEMBL8336438 | 0.89 | CNR2 (0.46) | MAPTHPGDKDM4EMEN1CYP1A2 | |
| SCHEMBL8633868 | 0.86 | MAPT (0.44) | MAPTHPGDKDM4EMEN1CYP1A2 | |
| SCHEMBL8635922 | 0.84 | MAPT (0.43) | MAPTHPGDKDM4EMEN1CYP1A2 | |
| SCHEMBL8632802 | 0.84 | MAPT (0.43) | MAPTHPGDKDM4EMEN1CYP1A2 | |
| SCHEMBL8336809 | 0.83 | CNR2 (0.47) | MAPTHPGDKDM4EMEN1CYP1A2 | |
| SCHEMBL8634148 | 0.83 | MEN1 (0.42) | MAPTHPGDKDM4EMEN1CYP1A2 | |
| SCHEMBL8340604 | 0.79 | MAPT (0.43) | MAPTHPGDKDM4EMEN1CYP1A2 | |
| SCHEMBL9002662 | 0.78 | MAPT (0.42) | MAPTHPGDKDM4EMEN1CYP1A2 | |
| SCHEMBL8339909 | 0.78 | CNR2 (0.45) | MAPTHPGDKDM4EMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747524-A | BENZOTHIOPHENES AND BENZOFURANS | ELI LILLY AND COMPANY (US) | 1998-05-05 | — | — | US | disclosed |