Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 5/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632802 | 0.96 | MAPT (0.43) | MAPTKDM4EMEN1CYP1A2CYP2D6 | |
| SCHEMBL8634790 | 0.90 | MAPT (0.48) | MAPTKDM4EMEN1CYP1A2CYP2D6 | |
| SCHEMBL8637426 | 0.84 | MAPT (0.47) | MAPTKDM4EMEN1CYP1A2CYP2D6 | |
| SCHEMBL7772092 | 0.84 | ESR1 (0.56) | CYP1A2CYP2D6ESR1ESR2 | |
| SCHEMBL8633868 | 0.83 | MAPT (0.44) | MAPTKDM4EMEN1CYP1A2CYP2D6 | |
| SCHEMBL8340639 | 0.82 | CNR2 (0.41) | MAPTKDM4EMEN1CYP1A2CYP2D6 | |
| SCHEMBL8634148 | 0.81 | MEN1 (0.42) | MAPTKDM4EMEN1CYP1A2CYP2D6 | |
| SCHEMBL8336035 | 0.81 | CNR2 (0.41) | MAPTKDM4EMEN1CYP1A2CYP2D6 | |
| SCHEMBL8336809 | 0.80 | CNR2 (0.47) | MAPTKDM4EMEN1CYP1A2CYP2D6 | |
| SCHEMBL8336383 | 0.77 | CNR2 (0.40) | MAPTKDM4EMEN1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747524-A | BENZOTHIOPHENES AND BENZOFURANS | ELI LILLY AND COMPANY (US) | 1998-05-05 | — | — | US | disclosed |