Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8336438 | 0.89 | CNR2 (0.46) | CNR2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8340604 | 0.87 | MAPT (0.43) | CNR2ALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL8336291 | 0.85 | MAPT (0.43) | CNR2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8333998 | 0.80 | CNR2 (0.41) | CNR2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8339168 | 0.80 | MCL1 (0.38) | CNR2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8336809 | 0.79 | CNR2 (0.47) | CNR2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8336077 | 0.79 | MCL1 (0.40) | CNR2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8339905 | 0.79 | HTR1A (0.46) | CNR2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8335085 | 0.78 | MAPT (0.44) | CNR2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8637426 | 0.78 | MAPT (0.47) | CNR2ALDH1A1MAPTMAOBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948796-A | OSTEOPOROSIS, CANCER, CARDIOVASCULAR DISORDERS | ELI LILLY AND COMPANY (US) | 1999-09-07 | — | — | US | disclosed |