Bromide

Bromide

SCHEMBL863747

Br.Br.CC1=C(C)C(C)(C)C([Ti]C2=C(C)C(C)=C(C)C2(C)C)=C1C

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2381967 0.97 CTSD (0.33) CTSD
Fluoride SCHEMBL864718 0.94 CTSD (0.32) CTSD
Hydrochloric Acid SCHEMBL396675 0.94 CTSD (0.32) CTSD
SCHEMBL4577188 0.94 CTSD (0.32) CTSD
Iodide SCHEMBL863901 0.94 CTSD (0.32) CTSD
Ethylene SCHEMBL216784 0.92 CTSD (0.36) CTSD
Chloromethane SCHEMBL7611586 0.92 CTSD (0.31) CTSD
Carbon Monoxide SCHEMBL863259 0.90 CTSD (0.34) CTSD
Acetaldehyde SCHEMBL10325496 0.85 CTSD (0.32) CTSD
Biphenyl SCHEMBL821668 0.80 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120076696-A1 Apparatus for hydrogenation and method for hydrogenating conjugated diene polymer by employing the apparatus CHI-MEI CORPORATION 2012-03-29 US disclosed
US-20110086978-A1 Apparatus for hydrogenation and method for hydrogenating conjugated diene polymer by employing the apparatus CHI-MEI CORPORATION 2011-04-14 US disclosed
US-20080262161-A1 Apparatus for hydrogenation and method for hydrogenating conjugated diene polymer by employing the apparatus CHI-MEI CORPORATION 2008-10-23 US disclosed
US-6313230-B1 HYDROGENATING CONJUGATED DIENE POLYMERS IN PRESENCE OF HYDROGEN AND A HYDROGENATION CATALYST FORMULATION COMPRISING TITANIUM COMPOUND, SILYL HYDRIDE COMPOUND, POLYSILOXANE, SILAZAN COMPOUND, AND METALLIC COMPOUND INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2001-11-06 US disclosed
US-6175025-B1 Process for synthesizing metallocene compounds ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2001-01-16 US disclosed