Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.42 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.42 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776736 | 0.74 | SMN1; SMN2 (0.58) | MAPTKMT2AALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL30441322 | 0.74 | ALDH1A1 (0.54) | MAPTKMT2AALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL25803089 | 0.73 | GSK3B (0.67) | MAPTKMT2AALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL523476 | 0.72 | PLOD2 (0.69) | MAPTKMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL3543531 | 0.72 | SMN1; SMN2 (0.63) | MAPTKMT2AALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL9630807 | 0.71 | PLOD2 (0.67) | MAPTKMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL9565951 | 0.71 | PLOD2 (0.67) | MAPTKMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL10613054 | 0.71 | PLOD2 (0.67) | MAPTKMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL9654173 | 0.71 | PLOD2 (0.67) | MAPTKMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL30846025 | 0.71 | PLOD2 (0.67) | MAPTKMT2AALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753688-A | ANTIINFLAMMATORY | TALLEY JOHN J (US) | 1998-05-19 | — | — | US | disclosed |