Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 11/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | RARG | P13631 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | RPA1 | P27694 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8830183 | 0.87 | RORC (0.52) | RORCCYP1A2HIF1ARARGKDM4E | |
| SCHEMBL30212115 | 0.87 | RORC (0.52) | RORCCYP1A2HIF1ARARGKDM4E | |
| SCHEMBL10663975 | 0.86 | RORC (0.51) | RORCCYP1A2HIF1ARARGKDM4E | |
| Potassium SCHEMBL10663990 | 0.86 | RORC (0.51) | RORCCYP1A2HIF1ARARGKDM4E | |
| SCHEMBL8636450 | 0.85 | KMT2A (0.48) | RORCCYP1A2RARGSMN1; SMN2MAPT | |
| SCHEMBL24047601 | 0.84 | CYP1A2 (0.45) | RORCCYP1A2HIF1ARARGKDM4E | |
| SCHEMBL9569710 | 0.84 | RORC (0.46) | RORCCYP1A2HIF1ARARGKDM4E | |
| SCHEMBL26074925 | 0.84 | CYP1A2 (0.45) | RORCCYP1A2HIF1ARARGKDM4E | |
| SCHEMBL30626334 | 0.84 | CYP1A2 (0.45) | RORCCYP1A2HIF1ARARGKDM4E | |
| SCHEMBL8830115 | 0.84 | RORC (0.44) | RORCRARGKDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519140-B1 | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acids, esters and salts thereof, and intermediates used in this method | HYBRINOVA (FR) | 1998-07-29 | — | — | EP | disclosed |
| US-5304672-A | Intermediates for pollen suppressants | ORSAN (FR) | 1994-04-19 | — | — | US | disclosed |
| US-5183891-A | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acid, esters and salts thereof, and intermediates used in their preparation | ORSAN (FR) | 1993-02-02 | — | — | US | disclosed |
| EP-0519140-A1 | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acid, esters and salts thereof, and intermediates used in their preparation | HYBRINOVA (FR) | 1992-12-23 | — | — | EP | disclosed |