Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RARG | P13631 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641097 | 0.90 | RORC (0.49) | RORCCYP1A2KMT2AMAPTTP53 | |
| SCHEMBL8637313 | 0.89 | RORC (0.52) | RORCKMT2AMAPTRARGTP53 | |
| SCHEMBL9338863 | 0.88 | CYP1A2 (0.43) | RORCCYP1A2HIF1AABCB1KMT2A | |
| SCHEMBL9401238 | 0.88 | MAPT (0.43) | RORCCYP1A2HIF1AABCB1KMT2A | |
| SCHEMBL8639493 | 0.88 | CCR2 (0.45) | RORCKMT2AMAPTRARGTP53 | |
| SCHEMBL124027 | 0.87 | MALT1 (0.41) | RORCCYP1A2HIF1AABCB1KMT2A | |
| SCHEMBL8634593 | 0.87 | CYP1A2 (0.44) | RORCCYP1A2HIF1AABCB1KMT2A | |
| SCHEMBL8830130 | 0.86 | CYP1A2 (0.41) | RORCCYP1A2HIF1AABCB1KMT2A | |
| SCHEMBL8636360 | 0.85 | RORC (0.46) | RORCCYP1A2KMT2AMAPTTP53 | |
| SCHEMBL8830007 | 0.85 | RORC (0.44) | RORCABCB1KMT2AMAPTRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530063-A1 | Pollen suppressant for dicotyledon plants comprising a 5-oxy-substituted cinnoline | ORSAN (FR) | 1993-03-03 | — | — | EP | disclosed |
| EP-0530064-A1 | Pollen suppressant for Liliopsida plants comprising a 5-oxy-substituted cinnoline | HYBRINOVA (FR) | 1993-03-03 | — | — | EP | disclosed |
| US-5129940-A | Antifertility agents for Liliopsida | ORSAN (FR) | 1992-07-14 | — | — | US | disclosed |