SCHEMBL8637525

SCHEMBL8637525

COC(=O)C(OC1CCCCO1)C(c1ccccc1)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 12/20 0.60
SLC6A2 P23975 2/20 0.44
SLC6A4 P31645 1/20 0.44
DHFR P00374 1/20 0.44
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
TSHR P16473 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
HPGD P15428 2/20 0.42
GAA P10253 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL8634737 0.87 SLC6A3 (0.46) SLC6A3LMNATDP1HPGDGAA
SCHEMBL14233517 0.86 SLC6A3 (0.61) SLC6A3SLC6A2SLC6A4DHFRALDH1A1
SCHEMBL14211627 0.86 SLC6A3 (0.61) SLC6A3SLC6A2SLC6A4DHFRALDH1A1
SCHEMBL1743566 0.86 SLC6A3 (0.61) SLC6A3SLC6A2SLC6A4DHFRALDH1A1
SCHEMBL8633697 0.79 SLC6A3 (0.42) SLC6A3ALDH1A1LMNAHPGDKMT2A
SCHEMBL3881607 0.78 SLC6A3 (0.51) SLC6A3GAA
SCHEMBL10391386 0.77 SLC6A3 (0.49) SLC6A3ALDH1A1LMNATSHRTDP1
SCHEMBL5570406 0.76 SLC6A3 (0.49) SLC6A3SLC6A2SLC6A4ALDH1A1TSHR
SCHEMBL14438434 0.76 SLC6A3 (0.49) SLC6A3SLC6A2SLC6A4ALDH1A1TSHR
SCHEMBL11719808 0.75 SLC6A3 (0.46) SLC6A3TDP1HPGDGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5760235-A DIPEPTIDES BASED ON PROLINE OR PIPECOLIC ACID AND ARGININE ALDEHYDE GYOGYSZERKUTATO INTEZET KFT. (HU) 1998-06-02 US disclosed
EP-0629212-B1 NEW ANTICOAGULANT PEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS WELL AS A PROCESS FOR THE PREPARATION THEREOF GYOGYSZERKUTATO INTEZET (HU) 1997-10-08 EP disclosed
EP-0629212-A1 NEW ANTICOAGULANT PEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS WELL AS A PROCESS FOR THE PREPARATION THEREOF. GYOGYSZERKUTATO INTEZET (HU) 1994-12-21 EP disclosed
WO-1993018060-A1 NEW ANTICOAGULANT PEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS WELL AS A PROCESS FOR THE PREPARATION THEREOF Gyógyszerkutató Intézet Kft. (HU) 1993-09-16 WO disclosed