SCHEMBL8637537

SCHEMBL8637537

CCOC(=O)C(Cl)=Cc1cc(C2CCCC(C(N)=O)=C2C(N)=O)ccc1Cl

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 5/20 0.32
SLC6A3 Q01959 5/20 0.32
SLC6A2 P23975 4/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
ALDH1A1 P00352 1/20 0.30
KDM4E B2RXH2 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8635223 0.77 SLC6A2 (0.31) SLC6A4SLC6A3SLC6A2
SCHEMBL7762961 0.77 NPSR1 (0.39) KMT2ALMNAMAPTHPGDALDH1A1
SCHEMBL7967762 0.77 NPSR1 (0.39) KMT2ALMNAMAPTHPGDALDH1A1
SCHEMBL7018839 0.72 LMNA (0.40) MEN1KMT2ALMNAMAPTHPGD
SCHEMBL7089765 0.72 LMNA (0.40) MEN1KMT2ALMNAMAPTHPGD
SCHEMBL7931186 0.71 KMT2A (0.42) KMT2AMAPTHPGDALDH1A1KDM4E
SCHEMBL7931184 0.71 KMT2A (0.42) KMT2AMAPTHPGDALDH1A1KDM4E
SCHEMBL8304677 0.69 NPSR1 (0.50) KMT2ALMNA
SCHEMBL7017572 0.69 MAPT (0.41) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL7020494 0.69 MAPT (0.41) MEN1KMT2AMAPTHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5817603-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-10-06 US disclosed