SCHEMBL7089765

SCHEMBL7089765

CCOC(=O)/C(Cl)=C/c1cc(N)ccc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.40
MAOA P21397 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 1/20 0.40
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
CHRM2 P08172 1/20 0.38
CHRM3 P20309 1/20 0.38
HTR2C P28335 1/20 0.38
CHRNA4 P43681 1/20 0.38
HTR3A P46098 1/20 0.38
KCNH2 Q12809 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
HPGD P15428 3/20 0.37
MAPT P10636 5/20 0.36
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36
PLIN1 O60240 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7018839 1.00 LMNA (0.40) LMNAMAOACYP1A2CYP3A4MEN1
SCHEMBL9551025 0.84 GAA (0.41) CYP3A4MEN1KMT2AMAPTTSHR
SCHEMBL9551024 0.84 GAA (0.41) CYP3A4MEN1KMT2AMAPTTSHR
SCHEMBL7017572 0.83 MAPT (0.41) MEN1KMT2AHPGDMAPTTSHR
SCHEMBL7020494 0.83 MAPT (0.41) MEN1KMT2AHPGDMAPTTSHR
SCHEMBL7111946 0.81 HPGD (0.38) LMNACYP1A2MEN1KMT2AHPGD
SCHEMBL7111942 0.81 HPGD (0.38) LMNACYP1A2MEN1KMT2AHPGD
SCHEMBL7931186 0.81 KMT2A (0.42) CYP1A2CYP3A4KMT2AHPGDMAPT
SCHEMBL7931184 0.81 KMT2A (0.42) CYP1A2CYP3A4KMT2AHPGDMAPT
SCHEMBL7900595 0.80 GLO1 (0.49) LMNAKMT2AMAPTSMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030130123-A1 2-Phenyl-2h-pyridazine-3-ones BASF AKTIENGESELLSCHAFT (DE) 2003-07-10 US disclosed
US-20010031865-A1 Substituted 3-phenyluracils KLINTZ RALF (DE) 2001-10-18 US disclosed
US-6239074-B1 HERBICIDES, INSECTICIDES BASF AKTIENGESELLSCHAFT (DE) 2001-05-29 US disclosed
EP-0666848-B1 SUBSTITUTED N-PHENYLGLUTARIMIDES AND N-PHENYLGLUTARIC ACID AMIDES, THEIR PREPARATION AND USE IN AGRICULTURE BASF AG (DE) 1998-12-30 EP disclosed
US-5698494-A Substituted N-phenylglutarimides and N-phenylglutaramides, their preparation and use BASF AKTIENGESELLSCHAFT (DE) 1997-12-16 US disclosed
EP-0666848-A1 SUBSTITUTED N-PHENYLGLUTARIMIDES AND N-PHENYLGLUTARIC ACID AMIDES, THEIR PREPARATION AND USE IN AGRICULTURE BASF Aktiengesellschaft (DE) 1995-08-16 EP disclosed
EP-0604491-A1 SUBSTITUTED 3-PHENYLURACILS AS HERBICIDES BASF Aktiengesellschaft (DE) 1994-07-06 EP disclosed
WO-1994010147-A1 SUBSTITUTED N-PHENYLGLUTARIMIDES AND N-PHENYLGLUTARIC ACID AMIDES, THEIR PREPARATION AND USE IN AGRICULTURE BASF AKTIENGESELLSCHAFT (DE) 1994-05-11 WO disclosed
WO-1993006090-A1 SUBSTITUTED 3-PHENYLURACILS AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1993-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030130123-A1 2-Phenyl-2h-pyridazine-3-ones CNPY2, CBR3, CBR1 LMNA 4129/4885MAOA 2522/4885CYP1A2 45/4885
US-20010031865-A1 Substituted 3-phenyluracils CCR1, CCR6, CCR3 LMNA 1409/4885MAOA 3441/4885CYP1A2 2240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.