SCHEMBL8637568

SCHEMBL8637568

CC(C)(C)NS(=O)(=O)c1cscc1Br

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 2/20 0.38
MAPT P10636 3/20 0.37
LMNA P02545 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 5/20 0.36
PARG Q86W56 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
MAPK1 P28482 1/20 0.33
POLB P06746 1/20 0.33
ALOX5AP P20292 2/20 0.32
BRD4 O60885 1/20 0.31
BRD2 P25440 1/20 0.31
BRD3 Q15059 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8231680 0.76 CA1 (0.41)
SCHEMBL10462729 0.73 NSD2 (0.38) NSD2MAPTLMNASMN1; SMN2KDM4E
SCHEMBL10464423 0.73 NSD2 (0.35) NSD2MAPTLMNASMN1; SMN2KDM4E
SCHEMBL12319506 0.73 PTGS2 (0.33)
SCHEMBL264098 0.71 CA1 (0.52) NSD2MAPTLMNASMN1; SMN2KDM4E
SCHEMBL20511875 0.70 NSD2 (0.50) NSD2MAPTLMNASMN1; SMN2KDM4E
SCHEMBL9577139 0.69 MAPT (0.41) NSD2MAPTLMNASMN1; SMN2KDM4E
SCHEMBL4970716 0.69
SCHEMBL10565221 0.68 NSD2 (0.32) NSD2MAPTLMNASMN1; SMN2KDM4E
SCHEMBL8645010 0.68 SMN1; SMN2 (0.40) NSD2MAPTLMNASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5726127-A Thiophenesulfonylurea derivatives and herbicidal composition containing the same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1998-03-10 US disclosed
EP-0728133-A1 NOVEL THIOPHENESULFONYLUREA DERIVATIVES AND HERBICIDAL COMPOSITION CONTAINING THE SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1996-08-28 EP disclosed
WO-1995013276-A1 NOVEL THIOPHENESULFONYLUREA DERIVATIVES AND HERBICIDAL COMPOSITION CONTAINING THE SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-05-18 WO disclosed
US-4935528-A HERBICIDES ISHIHARA SANGYO KAISHA LTD. (JP) 1990-06-19 US disclosed
US-4822402-A NONPHYTOTOXIC POSTEMERGENCE WEED CONTROL IN PADDY RICE FIELDS ISHIHARA SANGYO KAISHA LTD. (JP) 1989-04-18 US disclosed
US-4701535-A CHEMICAL INTERMEDIATES FOR HERBICIDES, PLANT GROWTH REGULATOR E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-10-20 US disclosed
CN-86103880-A Contain herbicide of thiophene sulfonamide compounds and preparation method thereof 1987-01-21 CN disclosed
US-4599103-A PRE-AND POSTEMERGENCE HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-07-08 US disclosed
US-4481029-A HERBICIDES, PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-11-06 US disclosed