Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | NSD2 | O96028 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PARG | Q86W56 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463947 | 0.81 | ALDH1A1 (0.40) | SMN1; SMN2KDM4ELMNAMAPTMEN1 | |
| SCHEMBL10616070 | 0.80 | NSD2 (0.46) | SMN1; SMN2KDM4ELMNAMAPTMEN1 | |
| SCHEMBL10465325 | 0.80 | SMN1; SMN2 (0.36) | SMN1; SMN2KDM4ELMNAMAPTMEN1 | |
| SCHEMBL8229612 | 0.79 | CA1 (0.45) | HPGDPOLBL3MBTL1EDNRAEDNRB | |
| SCHEMBL7265688 | 0.77 | LMNA (0.37) | SMN1; SMN2KDM4ELMNAMAPTMEN1 | |
| SCHEMBL28762591 | 0.77 | EDNRB (0.39) | SMN1; SMN2KDM4ELMNAMAPTMEN1 | |
| SCHEMBL9663862 | 0.76 | ALDH1A1 (0.49) | SMN1; SMN2KDM4ELMNAMAPTMEN1 | |
| SCHEMBL19095461 | 0.76 | MAPT (0.36) | SMN1; SMN2KDM4ELMNAMAPTMEN1 | |
| SCHEMBL1927724 | 0.75 | LMNA (0.38) | LMNAMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL9843392 | 0.74 | POLB (0.34) | POLBEDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726127-A | Thiophenesulfonylurea derivatives and herbicidal composition containing the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-03-10 | — | — | US | disclosed |
| WO-1995013276-A1 | NOVEL THIOPHENESULFONYLUREA DERIVATIVES AND HERBICIDAL COMPOSITION CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-05-18 | — | — | WO | disclosed |
| EP-0207609-B1 | HERBICIDAL THIOPHENESULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-01-08 | — | — | EP | disclosed |
| US-4877440-A | Thiophenesulfonamide herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-31 | — | — | US | disclosed |
| US-4743290-A | Thiophenesulfonamide herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-05-10 | — | — | US | disclosed |
| EP-0207609-A1 | Herbicidal thiophenesulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-01-07 | — | — | EP | disclosed |