Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.40 |
| ▸ | RARG | P13631 | 9/20 | 0.40 |
| ▸ | RARA | P10276 | 8/20 | 0.40 |
| ▸ | RXRA | P19793 | 6/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 3/20 | 0.32 |
| ▸ | RXRG | P48443 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6378018 | 0.81 | RARB (0.49) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL6340282 | 0.77 | RARB (0.41) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL19251649 | 0.76 | RARB (0.53) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL19342932 | 0.75 | RARB (0.68) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL7713094 | 0.70 | CYP3A4 (0.41) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL7751123 | 0.68 | RXRA (0.46) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL7714910 | 0.68 | RARB (0.58) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL6378170 | 0.68 | RARB (0.52) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL7751295 | 0.68 | RARB (0.51) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL2912775 | 0.68 | RARB (0.51) | RARBRARGRARARXRACYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661258-B1 | Biaromatic propynyl compounds, pharmaceutical compositions and cosmetics containing them and their uses | CIRD GALDERMA (FR) | 1998-04-08 | — | — | EP | disclosed |