Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17778606 | 0.82 | MAPT (0.54) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9850441 | 0.80 | ALDH1A1 (0.67) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL17776539 | 0.77 | MEN1 (0.64) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL30660950 | 0.76 | MAPT (0.61) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL19699516 | 0.74 | MAPT (0.54) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL31565319 | 0.72 | HDAC6 (0.59) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL14360604 | 0.72 | HDAC6 (0.59) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL17755003 | 0.70 | ALDH1A1 (0.46) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8473366 | 0.69 | MAPT (0.52) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL31565248 | 0.69 | MEN1 (0.51) | MAPTALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |