Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17778606 | 0.84 | MAPT (0.54) | ALDH1A1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL4866729 | 0.81 | TDP1 (0.73) | ALDH1A1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL30660950 | 0.80 | MAPT (0.61) | ALDH1A1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL29728211 | 0.80 | ALDH1A1 (1.00) | ALDH1A1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL4865337 | 0.80 | ALDH1A1 (1.00) | ALDH1A1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL8637798 | 0.80 | MAPT (0.49) | ALDH1A1HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL17776539 | 0.79 | MEN1 (0.64) | ALDH1A1LMNAMAPTKDM4EPOLB | |
| SCHEMBL31565319 | 0.77 | HDAC6 (0.59) | ALDH1A1HTTSMN1; SMN2MAPTKDM4E | |
| SCHEMBL14360604 | 0.77 | HDAC6 (0.59) | ALDH1A1HTTSMN1; SMN2MAPTKDM4E | |
| SCHEMBL4861625 | 0.77 | ALDH1A1 (0.64) | ALDH1A1HTTLMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |