Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | YAP1 | P46937 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326259 | 0.84 | YAP1 (0.53) | ITGB3ITGA2BCTSSCTSKYAP1 | |
| SCHEMBL7326264 | 0.78 | ITGB3 (0.46) | F10ITGB3ITGA2BCTSSCTSK | |
| SCHEMBL7327020 | 0.78 | ACACB (0.47) | F10ITGB3ITGA2BACACB | |
| SCHEMBL7327023 | 0.78 | ACACB (0.47) | F10ITGB3ITGA2BACACB | |
| Hydrochloric Acid SCHEMBL7329132 | 0.77 | F10 (0.47) | F10ITGB3ITGA2BACACB | |
| Hydrochloric Acid SCHEMBL7329134 | 0.77 | F10 (0.47) | F10ITGB3ITGA2BACACB | |
| SCHEMBL8605366 | 0.77 | F10 (0.48) | F10ITGB3ITGA2BACACB | |
| SCHEMBL7449579 | 0.77 | F10 (0.48) | F10ITGB3ITGA2BACACB | |
| SCHEMBL7401785 | 0.76 | ITGB3 (0.55) | ITGB3ITGA2BYAP1 | |
| SCHEMBL7404574 | 0.76 | ITGB3 (0.64) | ITGB3ITGA2BYAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| US-5728701-A | INHIBIT PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |