Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641147 | 0.77 | ESR1 (0.35) | ESR1ESR2CA4PAX8TSHR | |
| SCHEMBL8644592 | 0.77 | MAPT (0.36) | ESR1ESR2PAX8TSHRHPGD | |
| SCHEMBL25193347 | 0.74 | ESR1 (0.38) | ESR1ESR2CA4PAX8TSHR | |
| SCHEMBL25183121 | 0.74 | ESR1 (0.38) | ESR1ESR2CA4PAX8TSHR | |
| SCHEMBL10608533 | 0.72 | TSHR (0.47) | CA4TSHRPOLB | |
| SCHEMBL9118568 | 0.70 | PAX8 (0.34) | ESR1ESR2PAX8HPGD | |
| SCHEMBL646249 | 0.69 | CA4 (0.43) | ESR1ESR2CA4TSHRPOLB | |
| SCHEMBL25178948 | 0.69 | ESR1 (0.33) | ESR1ESR2 | |
| SCHEMBL1024518 | 0.69 | ESR1 (0.39) | ESR1ESR2CA4TSHRPOLB | |
| SCHEMBL1023520 | 0.69 | ESR1 (0.39) | ESR1ESR2CA4TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641820-B1 | Organosilicon polymer and process for the preparation thereof | TOSHIBA SILICONE (JP) | 1998-08-12 | — | — | EP | disclosed |
| US-5489662-A | Process for the preparation of organosilicon polymer | TOSHIBA SILICONE CO., LTD. (JP) | 1996-02-06 | — | — | US | disclosed |
| EP-0641820-A1 | Process for the preparation of organosilicon polymer | TOSHIBA SILICONE CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |