Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5494133 | 0.76 | PAX8 (0.33) | PAX8ESR1ESR2HPGD | |
| SCHEMBL9652309 | 0.70 | ESR1 (0.39) | PAX8ESR1ESR2HPGDCES2 | |
| SCHEMBL22200088 | 0.70 | ESR1 (0.39) | PAX8ESR1ESR2HPGDCES2 | |
| SCHEMBL8637893 | 0.70 | ESR1 (0.35) | PAX8ESR1ESR2HPGD | |
| SCHEMBL7900984 | 0.69 | ESR1 (0.43) | PAX8ESR1ESR2HPGDCES2 | |
| SCHEMBL21295309 | 0.67 | ESR1 (0.34) | PAX8ESR1ESR2HPGDMAPT | |
| SCHEMBL8572488 | 0.66 | ESR1 (0.34) | ESR1ESR2 | |
| SCHEMBL2233576 | 0.66 | ESR1 (0.39) | ESR1ESR2MAPT | |
| SCHEMBL211428 | 0.66 | ESR1 (0.39) | ESR1ESR2MAPT | |
| SCHEMBL16486462 | 0.66 | CES2 (0.42) | PAX8ESR1CES2CES1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436303-A | Solvent resistance, tack and peel adhesion properties | GENERAL ELECTRIC COMPANY (US) | 1995-07-25 | — | — | US | disclosed |
| EP-0552917-A1 | Fluorosilicone pressure sensitive adhesives | GENERAL ELECTRIC COMPANY (US) | 1993-07-28 | — | — | EP | disclosed |