Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641792 | 0.86 | TDP1 (0.39) | TSHRTDP1 | |
| SCHEMBL8641789 | 0.86 | TDP1 (0.39) | TSHRTDP1 | |
| SCHEMBL21049917 | 0.81 | TSHR (0.37) | TSHRTP53TDP1 | |
| SCHEMBL8641772 | 0.80 | TDP1 (0.43) | TDP1 | |
| SCHEMBL8641794 | 0.80 | TDP1 (0.43) | TDP1 | |
| SCHEMBL3289373 | 0.76 | TSHR (0.48) | TSHRTP53TDP1 | |
| SCHEMBL6988924 | 0.69 | TSHR (0.37) | TSHRTP53TDP1 | |
| SCHEMBL12207660 | 0.68 | TSHR (0.43) | TSHRTP53TDP1 | |
| SCHEMBL3103434 | 0.66 | ACHE (0.40) | TSHRTP53TDP1 | |
| SCHEMBL6985563 | 0.65 | TSHR (0.40) | TSHRTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686143-B1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | CIBA GEIGY AG (CH) | 1998-08-12 | — | — | EP | disclosed |
| US-5627215-A | Unsaturate amino compounds for use as anticancer and antiprotozoic agent | CIBA-GEIGY CORPORATION (US) | 1997-05-06 | — | — | US | disclosed |
| EP-0686143-A1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | Novartis AG (CH) | 1995-12-13 | — | — | EP | disclosed |
| WO-1995018091-A1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | CIBA-GEIGY AG (CH) | 1995-07-06 | — | — | WO | disclosed |