Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8638289 | 0.90 | ALDH1A1 (0.52) | ALDH1A1LMNAFEN1MAPTPTK2B | |
| SCHEMBL5703139 | 0.83 | ALDH1A1 (0.58) | ALDH1A1LMNAFEN1MAPTPTK2B | |
| SCHEMBL5703150 | 0.77 | LMNA (0.48) | ALDH1A1LMNAFEN1MAPTPTK2B | |
| SCHEMBL3316731 | 0.76 | ALDH1A1 (0.50) | ALDH1A1LMNAFEN1MAPTPTK2B | |
| SCHEMBL28263768 | 0.76 | CA12 (0.52) | ALDH1A1LMNAFEN1MAPTPTK2B | |
| SCHEMBL27920412 | 0.76 | ALDH1A1 (0.50) | ALDH1A1LMNAFEN1MAPTPTK2B | |
| SCHEMBL21295475 | 0.76 | ALDH1A1 (0.45) | ALDH1A1LMNAFEN1MAPTPTK2B | |
| SCHEMBL28340585 | 0.74 | ALDH1A1 (0.58) | ALDH1A1LMNAFEN1MAPTPTK2B | |
| SCHEMBL23926925 | 0.74 | ALDH1A1 (0.44) | ALDH1A1LMNAFEN1MAPTPTK2B | |
| SCHEMBL3979030 | 0.72 | ALDH1A1 (0.45) | ALDH1A1LMNAFEN1MAPTPTK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519140-B1 | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acids, esters and salts thereof, and intermediates used in this method | HYBRINOVA (FR) | 1998-07-29 | — | — | EP | disclosed |
| US-5304672-A | Intermediates for pollen suppressants | ORSAN (FR) | 1994-04-19 | — | — | US | disclosed |
| US-5183891-A | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acid, esters and salts thereof, and intermediates used in their preparation | ORSAN (FR) | 1993-02-02 | — | — | US | disclosed |
| EP-0519140-A1 | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acid, esters and salts thereof, and intermediates used in their preparation | HYBRINOVA (FR) | 1992-12-23 | — | — | EP | disclosed |