SCHEMBL8638358

SCHEMBL8638358

CC(C)c1ccc(C(C)C)c(Cc2cc(C(C)C)ccc2C(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.40
TRPA1 O75762 2/20 0.39
PTGS1 P23219 1/20 0.39
CACNA1C Q13936 1/20 0.39
ALDH1A1 P00352 2/20 0.38
GAA P10253 1/20 0.38
ALOX12 P18054 1/20 0.38
HTT P42858 1/20 0.38
HIF1A Q16665 1/20 0.38
FABP3 P05413 2/20 0.36
FABP4 P15090 2/20 0.36
FABP5 Q01469 1/20 0.36
RNASEH1 O60930 1/20 0.35
HTR1D P28221 2/20 0.35
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
CHRM1 P11229 1/20 0.34
SLC6A2 P23975 1/20 0.34
ADRA1A P35348 1/20 0.34
HTR2B P41595 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11768020 0.86 GPR55 (0.42) LMNATRPA1PTGS1CACNA1CALDH1A1
SCHEMBL605602 0.84 LMNA (0.39) LMNATRPA1PTGS1CACNA1CALDH1A1
SCHEMBL27383714 0.84 HSPA5 (0.52) LMNATRPA1PTGS1CACNA1CALDH1A1
SCHEMBL607135 0.83 ACE2 (0.42) LMNATRPA1PTGS1CACNA1CALDH1A1
SCHEMBL26137536 0.83 HTR1D (0.40) LMNATRPA1PTGS1CACNA1CALDH1A1
SCHEMBL5050256 0.82 FABP3 (0.41) LMNATRPA1PTGS1CACNA1CALDH1A1
SCHEMBL27383713 0.82 ESR1 (0.44) TRPA1PTGS1CACNA1CALDH1A1GAA
SCHEMBL8736923 0.81 LMNA (0.36) LMNATRPA1PTGS1CACNA1CALDH1A1
SCHEMBL27252554 0.81 PPARG (0.38) LMNATRPA1PTGS1CACNA1CALDH1A1
SCHEMBL26137530 0.81 CYP1A2 (0.47) LMNATRPA1PTGS1CACNA1CALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5723571-A POLYIMIDESILOXANE COPOLYMERS TOMOEGAWA PAPER CO., LTD. (JP) 1998-03-03 US disclosed