Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | BCL2 | P10415 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8638653 | 0.88 | KMT2A (0.43) | RORCNR3C1RXFP1RARGPLA2G2A | |
| SCHEMBL8637313 | 0.85 | RORC (0.52) | RORCRXFP1RARGTDP1 | |
| SCHEMBL9401238 | 0.79 | MAPT (0.43) | RORCRXFP1RARGLMNA | |
| SCHEMBL8636437 | 0.78 | MAPK1 (0.41) | RORCRXFP1 | |
| SCHEMBL30310934 | 0.77 | KMT2A (0.46) | RORCRARGLMNA | |
| SCHEMBL8830130 | 0.77 | CYP1A2 (0.41) | RORCRARGLMNA | |
| SCHEMBL26074802 | 0.77 | KMT2A (0.46) | RORCRARGLMNA | |
| SCHEMBL124027 | 0.76 | MALT1 (0.41) | RORCRARG | |
| SCHEMBL8641097 | 0.76 | RORC (0.49) | RORCLMNATDP1 | |
| SCHEMBL28971929 | 0.76 | CCR1 (0.39) | RORCRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519140-B1 | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acids, esters and salts thereof, and intermediates used in this method | HYBRINOVA (FR) | 1998-07-29 | — | — | EP | disclosed |
| US-5696055-A | USED IN INDUCING MALE STERILITY OR PRODUCING HYBRID SEEDS IN A GRAMINEOUS PLANT | HYBRINOVA S.A. (FR) | 1997-12-09 | — | — | US | disclosed |
| EP-0363236-B1 | Pollen suppressant comprising a 5-oxy- or amino-substituted cinnoline | HYBRINOVA (FR) | 1994-12-07 | — | — | EP | disclosed |
| US-5332716-A | Pollen suppressant comprising a 5-oxy- or amino-substituted cinnoline | E.I. DU PONT DE NEMOURS AND COMPANY | 1994-07-26 | — | — | US | disclosed |
| US-5304672-A | Intermediates for pollen suppressants | ORSAN (FR) | 1994-04-19 | — | — | US | disclosed |
| EP-0530064-A1 | Pollen suppressant for Liliopsida plants comprising a 5-oxy-substituted cinnoline | HYBRINOVA (FR) | 1993-03-03 | — | — | EP | disclosed |
| EP-0530063-A1 | Pollen suppressant for dicotyledon plants comprising a 5-oxy-substituted cinnoline | ORSAN (FR) | 1993-03-03 | — | — | EP | disclosed |
| US-5183891-A | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acid, esters and salts thereof, and intermediates used in their preparation | ORSAN (FR) | 1993-02-02 | — | — | US | disclosed |
| EP-0519140-A1 | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acid, esters and salts thereof, and intermediates used in their preparation | HYBRINOVA (FR) | 1992-12-23 | — | — | EP | disclosed |
| US-5129940-A | Antifertility agents for Liliopsida | ORSAN (FR) | 1992-07-14 | — | — | US | disclosed |
| US-5129939-A | Antifertility agents | ORSAN (FR) | 1992-07-14 | — | — | US | disclosed |
| EP-0363236-A1 | Pollen suppressant comprising a 5-oxy- or amino-substituted cinnoline | HYBRINOVA (FR) | 1990-04-11 | — | — | EP | disclosed |