Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
| ▸ | PTGIR | P43119 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635717 | 0.91 | NR1H2 (0.35) | SMN1; SMN2LMNATHRBGAACYP1A2 | |
| SCHEMBL8638883 | 0.89 | HTT (0.36) | SMN1; SMN2LMNATHRBGAAHPGD | |
| SCHEMBL8636447 | 0.86 | PLAU (0.36) | SMN1; SMN2LMNATHRBGAAHPGD | |
| SCHEMBL8634953 | 0.80 | PPARG (0.37) | GAAHPGDPOLBALDH1A3KMT2A | |
| SCHEMBL8907787 | 0.80 | PPARA (0.34) | SMN1; SMN2LMNATHRBGAACYP1A2 | |
| SCHEMBL8633489 | 0.78 | GABRA1 (0.34) | SMN1; SMN2LMNATHRBNPSR1POLB | |
| SCHEMBL8632153 | 0.76 | PLAU (0.35) | SMN1; SMN2LMNAGAAHPGDNPSR1 | |
| SCHEMBL8632346 | 0.76 | PPARG (0.40) | — | |
| SCHEMBL8631583 | 0.74 | NPC1 (0.41) | SMN1; SMN2LMNAHPGDNPSR1POLB | |
| SCHEMBL8635932 | 0.74 | ACACB (0.35) | GAACYP1A2CYP2D6CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648729-B1 | Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound | SUMITOMO CHEMICAL CO (JP) | 1998-07-15 | — | — | EP | disclosed |
| US-5698702-A | INTERMEDIATES FOR INSECTICIDES, ACARICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-16 | — | — | US | disclosed |
| US-5530015-A | Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-25 | — | — | US | disclosed |
| EP-0648729-A1 | Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-04-19 | — | — | EP | disclosed |