SCHEMBL8907787

SCHEMBL8907787

CCCc1cc(Sc2ccc(OC(C)C)cc2)ccc1OCC=C(Cl)Cl

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 4/20 0.34
PPARG P37231 3/20 0.34
NR1H2 P55055 4/20 0.34
NR1H3 Q13133 2/20 0.34
LMNA P02545 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
THRB P10828 1/20 0.32
HTT P42858 1/20 0.32
FFAR4 Q5NUL3 2/20 0.32
CYP1A2 P05177 1/20 0.31
GAA P10253 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
PTGIR P43119 1/20 0.31
PPARD Q03181 4/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8638883 0.91 HTT (0.36) LMNASMN1; SMN2THRBHTTFFAR4
SCHEMBL8635717 0.89 NR1H2 (0.35) PPARAPPARGNR1H2NR1H3LMNA
SCHEMBL8638417 0.88 HTT (0.36) PPARAPPARGNR1H2NR1H3LMNA
SCHEMBL8632253 0.85 PPARG (0.40) PPARAPPARGNR1H2PPARD
SCHEMBL8632153 0.83 PLAU (0.35) LMNASMN1; SMN2HTTFFAR4CYP1A2
SCHEMBL8635944 0.81 MTNR1A (0.35) LMNASMN1; SMN2THRBHTTGAA
SCHEMBL8634634 0.80 LTB4R (0.42) PPARAPPARGPPARD
SCHEMBL8638728 0.80 SMN1; SMN2 (0.33) LMNASMN1; SMN2THRBCYP1A2GAA
SCHEMBL8633489 0.76 GABRA1 (0.34) PPARAPPARGNR1H2NR1H3LMNA
SCHEMBL8632346 0.74 PPARG (0.40) PPARAPPARGNR1H2NR1H3PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed