SCHEMBL8638768

SCHEMBL8638768

Cc1ccc(N(c2ccc(C)cc2)c2ccc(CC(=O)Cc3ccc(N(c4ccc(C)cc4)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.51
TDP1 Q9NUW8 1/20 0.51
HPGD P15428 3/20 0.47
CNR2 P34972 2/20 0.47
CTBP2 P56545 1/20 0.46
CNR1 P21554 1/20 0.46
RAB9A P51151 2/20 0.44
NPC1 O15118 1/20 0.44
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
GAA P10253 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4940818 0.87 L3MBTL1 (0.62) L3MBTL1TDP1HPGDCTBP2RAB9A
SCHEMBL8642376 0.86 HPGD (0.46) L3MBTL1TDP1HPGDCNR2CTBP2
SCHEMBL28190787 0.86 ALDH1A1 (0.58) L3MBTL1TDP1HPGDCNR2CTBP2
SCHEMBL9607495 0.82 ABCC4 (0.56) HPGDCNR2CTBP2KMT2AMEN1
SCHEMBL279137 0.82 ABCC4 (0.56) HPGDCNR2CTBP2KMT2AMEN1
SCHEMBL7148258 0.81 L3MBTL1 (0.56) L3MBTL1TDP1HPGDCTBP2RAB9A
SCHEMBL11219229 0.79 L3MBTL1 (0.76) L3MBTL1TDP1CNR2CTBP2CNR1
SCHEMBL29001876 0.78 AOC3 (0.60) L3MBTL1TDP1CNR2CNR1RAB9A
SCHEMBL1411319 0.78 L3MBTL1 (0.62) L3MBTL1TDP1HPGDCTBP2RAB9A
SCHEMBL18371865 0.78 MEN1 (0.64) L3MBTL1TDP1HPGDCTBP2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0610912-B1 Polycarbonate polymer derived from dihydroxy compound having triphenylamine structure and process for producing the same MITSUBISHI GAS CHEMICAL CO (JP) 1998-08-12 EP disclosed
US-5428090-A Plastic molding materials MITSUBISHI GAS CHEMICAL CO., INC. (JP) 1995-06-27 US disclosed
EP-0610912-A2 Polycarbonate polymer derived from dihydroxy compound having triphenylamine structure and process for producing the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1994-08-17 EP disclosed