Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 3/20 | 0.77 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.75 |
| ▸ | QPCT | Q16769 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | NOS1 | P29475 | 2/20 | 0.64 |
| ▸ | LTA4H | P09960 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260489 | 0.94 | TBXAS1 (0.71) | CACNA1BTBXAS1NOS1KDM4ELMNA | |
| SCHEMBL12045305 | 0.94 | TBXAS1 (0.84) | CACNA1BTBXAS1QPCTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9996074 | 0.92 | TBXAS1 (0.82) | CACNA1BTBXAS1QPCTMEN1KMT2A | |
| SCHEMBL12045307 | 0.89 | TBXAS1 (0.82) | TBXAS1MEN1KMT2ANOS1KDM4E | |
| Hydrochloric Acid SCHEMBL9996079 | 0.88 | TBXAS1 (0.79) | TBXAS1MEN1KMT2AATMNOS1 | |
| SCHEMBL10476929 | 0.88 | TBXAS1 (0.79) | TBXAS1MEN1KMT2ANOS1KDM4E | |
| Hydrochloric Acid SCHEMBL2529362 | 0.88 | MEN1 (0.85) | TBXAS1QPCTMEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL9483473 | 0.87 | KMT2A (0.70) | TBXAS1QPCTMEN1KMT2AATM | |
| SCHEMBL10370478 | 0.86 | TBXAS1 (1.00) | TBXAS1MEN1KMT2ANOS1LTA4H | |
| Hydrochloric Acid SCHEMBL9996050 | 0.84 | TBXAS1 (0.97) | TBXAS1MEN1KMT2ANOS1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723492-A | LTA4 hydrolase inhibitor pharmaceutical compositions and methods of use | G.D. SEARLE & CO. (US) | 1998-03-03 | — | — | US | disclosed |
| US-5719306-A | ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |
| US-5280036-A | Containing 4h-1,24-triazole ring | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-18 | — | — | US | disclosed |
| US-5214064-A | Insecticides, nematocides, miticides | BASF AKTIENGESELLSCHAFT (DE) | 1993-05-25 | — | — | US | disclosed |
| EP-0289919-B1 | N-SUBSTITUTED AZOLES | BASF Aktiengesellschaft (DE) | 1993-03-17 | — | — | EP | disclosed |
| US-5187182-A | Insecticides, nematocides | BASF AKTIENGESELLSCHAFT (DE) | 1993-02-16 | — | — | US | disclosed |
| US-5185359-A | N-phenoxphenyloxymethyl substituted azoles and method for controlling pests therewith | BASF AKTIENGESELLSCHAFT (DE) | 1993-02-09 | — | — | US | disclosed |
| US-5116860-A | N-SUBSTITUTED AZOLES FOR COMBATING INSECTS, ARACHNIDS AND NEMATODES | BASF AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | disclosed |
| US-4943585-A | N-substituted azoles and insecticide, arachnicide, and nematocide compositions thereof | BASF AKTIENGESELLSCHAFT (DE) | 1990-07-24 | — | — | US | disclosed |
| EP-0289919-A2 | N-Substituted azoles | BASF Aktiengesellschaft (DE) | 1988-11-09 | — | — | EP | disclosed |