Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.71 |
| ▸ | NOS1 | P29475 | 4/20 | 0.71 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8638819 | 0.94 | CACNA1B (0.77) | TBXAS1NOS1CACNA1BKDM4ELMNA | |
| SCHEMBL10476929 | 0.94 | TBXAS1 (0.79) | TBXAS1NOS1KDM4ELMNACYP1A2 | |
| SCHEMBL12045307 | 0.93 | TBXAS1 (0.82) | TBXAS1NOS1KDM4ELMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL9996079 | 0.91 | TBXAS1 (0.79) | TBXAS1NOS1KDM4ELMNACYP1A2 | |
| SCHEMBL12045305 | 0.88 | TBXAS1 (0.84) | TBXAS1NOS1CACNA1BKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL9482169 | 0.88 | NOS1 (0.69) | TBXAS1NOS1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL9996074 | 0.87 | TBXAS1 (0.82) | TBXAS1NOS1CACNA1BKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL9482174 | 0.86 | ATP4A (0.70) | TBXAS1NOS1KDM4ELMNA | |
| SCHEMBL10370478 | 0.84 | TBXAS1 (1.00) | TBXAS1NOS1KDM4ELMNAALDH1A1 | |
| SCHEMBL12835094 | 0.83 | QPCT (0.89) | NOS1KDM4ELMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274867-A2 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1988-07-20 | — | — | EP | claimed |
| US-5459144-A | Enterovirus and rhinovirus antiviral, antiinflammatory and antagonist of platelet activating factor | SCHERING CORPORATION (US) | 1995-10-17 | — | — | US | disclosed |
| US-5272167-A | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1993-12-21 | — | — | US | disclosed |
| EP-0560407-A1 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1993-09-15 | — | — | EP | disclosed |
| WO-1991000858-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS | SCHERING CORPORATION (US) | 1991-01-24 | — | — | WO | disclosed |
| EP-0407217-A1 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1991-01-09 | — | — | EP | disclosed |
| US-4851423-A | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0274867-A2 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1988-07-20 | — | — | EP | disclosed |