Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.58 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.58 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL965839 | 0.88 | AGTR1 (0.67) | AGTR1AGTR2GP6PDE4APDE4B | |
| SCHEMBL18003201 | 0.88 | AGTR1 (0.61) | AGTR1AGTR2GP6 | |
| SCHEMBL28517678 | 0.86 | AGTR1 (0.59) | AGTR1AGTR2GP6 | |
| SCHEMBL4639444 | 0.86 | AGTR1 (0.59) | AGTR1AGTR2GP6 | |
| SCHEMBL8568897 | 0.86 | AGTR1 (0.59) | AGTR1AGTR2GP6 | |
| SCHEMBL3872329 | 0.83 | AGTR1 (0.59) | AGTR1AGTR2GP6 | |
| SCHEMBL7828008 | 0.83 | AGTR1 (0.64) | AGTR1AGTR2GP6 | |
| SCHEMBL649 | 0.82 | AGTR1 (0.58) | AGTR1AGTR2GP6 | |
| SCHEMBL1458517 | 0.82 | AGTR1 (0.56) | AGTR1AGTR2GP6 | |
| SCHEMBL17943651 | 0.81 | AGTR1 (0.62) | AGTR1AGTR2GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776964-A | HYPOTENSIVE AGENTS; ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-07 | — | — | US | disclosed |