Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 8/20 | 0.54 |
| ▸ | RXRA | P19793 | 7/20 | 0.54 |
| ▸ | RXRG | P48443 | 6/20 | 0.54 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | BAD | Q92934 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3408719 | 0.98 | RXRB (0.55) | RXRBRXRARXRGBCL2L1BAD | |
| SCHEMBL28739318 | 0.95 | RXRB (0.55) | RXRBRXRARXRGBCL2L1BAD | |
| SCHEMBL10863869 | 0.83 | ALDH1A1 (0.55) | RXRBRXRARXRGBCL2L1BAD | |
| SCHEMBL5659543 | 0.81 | RXRB (0.59) | RXRBRXRARXRGLMNASMN1; SMN2 | |
| SCHEMBL6662229 | 0.79 | ALDH1A1 (0.51) | RXRBRXRARXRGBCL2L1BAD | |
| SCHEMBL19212186 | 0.79 | RXRB (0.43) | RXRBRXRARXRGBCL2L1BAD | |
| SCHEMBL30150923 | 0.79 | RXRB (0.43) | RXRBRXRARXRGBCL2L1BAD | |
| SCHEMBL9181008 | 0.79 | ALDH1A1 (0.47) | RXRBRXRARXRGBCL2L1BAD | |
| SCHEMBL5753897 | 0.78 | BCL2L1 (0.53) | RXRBRXRARXRGBCL2L1BAD | |
| SCHEMBL8481831 | 0.77 | ALDH1A1 (0.44) | RXRBRXRARXRGBCL2L1BAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753662-A | TREATING DOPAMINERGIC SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1998-05-19 | — | — | US | disclosed |
| US-5684020-A | ANTIPSYCHOTICS, ANTIDEPRESSANTS, TREATMENT OF DYSFUNCTION OF DOPAMINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1997-11-04 | — | — | US | disclosed |
| US-5194437-A | Substituted with oxygen containing heterocycle, central nervous system disorders, neuroendocrine disorders | ADIR ET COMPAGNIE (FR) | 1993-03-16 | — | — | US | disclosed |