Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8141080 | 0.90 | EPHX1 (0.44) | EPHX1TRPM8TRPA1KCNA5ALDH1A1 | |
| SCHEMBL5680423 | 0.74 | TRPM8 (0.52) | EPHX1TRPM8TRPA1KCNA5ALDH1A1 | |
| SCHEMBL8148565 | 0.73 | — | — | |
| SCHEMBL8642189 | 0.72 | — | — | |
| SCHEMBL8639023 | 0.70 | EPHX1 (0.40) | EPHX1TRPM8TRPA1KCNA5ALDH1A1 | |
| SCHEMBL4389935 | 0.69 | TRPM8 (0.65) | EPHX1TRPM8TRPA1KCNA5ALDH1A1 | |
| SCHEMBL13465301 | 0.69 | TRPM8 (0.65) | EPHX1TRPM8TRPA1KCNA5ALDH1A1 | |
| SCHEMBL8991389 | 0.69 | EPHX1 (0.47) | EPHX1TRPM8TRPA1KCNA5ALDH1A1 | |
| SCHEMBL28280924 | 0.69 | TRPM8 (0.46) | EPHX1TRPM8TRPA1KCNA5ALDH1A1 | |
| SCHEMBL30604482 | 0.69 | TRPM8 (0.62) | EPHX1TRPM8TRPA1KCNA5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804569-A | ANTIINFLAMMATORY, ANTIARRHYMIC AND LOCAL ANESTHETIC AGENT | CLARION PHARMACEUTICALS INC. (US) | 1998-09-08 | — | — | US | disclosed |