Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694409 | 0.77 | EPHX1 (0.61) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL30604482 | 0.73 | TRPM8 (0.62) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL1030886 | 0.72 | EPHX1 (0.53) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL9951257 | 0.72 | EPHX1 (0.53) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL3274993 | 0.72 | EPHX1 (0.53) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| Menthol SCHEMBL2937643 | 0.72 | TRPM8 (0.81) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL9951715 | 0.72 | EPHX1 (0.53) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL2937641 | 0.71 | ALDH1A1 (0.57) | EPHX1TRPM8TRPA1KCNA5ALDH1A1 | |
| SCHEMBL2935357 | 0.71 | ALDH1A1 (0.57) | EPHX1TRPM8TRPA1KCNA5ALDH1A1 | |
| SCHEMBL851820 | 0.70 | EPHX1 (0.51) | EPHX1TRPM8TRPA1KCNA5TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721323-A1 | DIPHOSPHONIC ACID ESTERS AS TARTAR CONTROL AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1996-07-17 | — | — | EP | disclosed |
| US-5451401-A | Diphosphonic acid esters as tartar control agents | THE PROCTER & GAMBLE COMPANY (US) | 1995-09-19 | — | — | US | disclosed |
| WO-1995008979-A1 | DIPHOSPHONIC ACID ESTERS AS TARTAR CONTROL AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1995-04-06 | — | — | WO | disclosed |