Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.59 |
| ▸ | DRD4 | P21917 | 13/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | FADS1 | O60427 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820126 | 0.87 | DRD4 (0.70) | DRD2DRD4HTR1AHTR2A | |
| SCHEMBL7822562 | 0.83 | DRD4 (0.55) | DRD2DRD4HTR1AHTR2A | |
| SCHEMBL7821927 | 0.81 | DRD4 (0.60) | DRD2DRD4HTR1AHTR2A | |
| SCHEMBL7994734 | 0.81 | DRD4 (0.60) | DRD2DRD4HTR1AHTR2A | |
| SCHEMBL6907064 | 0.81 | DRD4 (0.60) | DRD2DRD4HTR1AHTR2A | |
| SCHEMBL6908454 | 0.77 | DRD4 (0.69) | DRD2DRD4HTR1AHTR2A | |
| SCHEMBL7812210 | 0.77 | DRD4 (0.69) | DRD2DRD4HTR1AHTR2A | |
| SCHEMBL7998001 | 0.77 | DRD4 (0.69) | DRD2DRD4HTR1AHTR2A | |
| SCHEMBL7820151 | 0.77 | DRD4 (0.52) | DRD2DRD4HTR1AHTR2A | |
| SCHEMBL8665307 | 0.77 | DRD4 (0.52) | DRD2DRD4HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874849-A1 | 2,7-SUBSTITUTED OCTAHYDRO-PYRROLO 1,2-A]PYRAZINE DERIVATIVES | PFIZER INC. (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997023482-A1 | 2,7-SUBSTITUTED OCTAHYDRO-PYRROLO[1,2-A]PYRAZINE DERIVATIVES | PFIZER INC. (US) | 1997-07-03 | — | — | WO | disclosed |