Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991097 | 0.90 | ALDH1A1 (0.55) | GAAALDH1A1SMN1; SMN2POLBPDE4A | |
| SCHEMBL6992040 | 0.89 | SLC6A4 (0.47) | GAAMAPTSMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL6995994 | 0.84 | GAA (0.41) | GAAALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL7465770 | 0.82 | GAA (0.37) | GAAALDH1A1MAPTSMN1; SMN2SLC6A2 | |
| SCHEMBL6998444 | 0.82 | GAA (0.45) | GAAALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL7490147 | 0.81 | GAA (0.40) | GAAALDH1A1MAPTSMN1; SMN2SLC6A2 | |
| SCHEMBL11816778 | 0.81 | GAA (0.42) | GAAALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL7487771 | 0.80 | KMT2A (0.37) | GAAALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7954832 | 0.79 | OPRM1 (0.44) | GAAALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11817118 | 0.79 | GAA (0.41) | GAAALDH1A1SLC6A2SLC6A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |