SCHEMBL863916

SCHEMBL863916

NNC(=O)c1ccc(OCc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.88
MAPT P10636 5/20 0.88
HTT P42858 2/20 0.72
MAPK1 P28482 1/20 0.72
NPC1 O15118 6/20 0.71
PARP10 Q53GL7 1/20 0.71
NR4A1 P22736 1/20 0.70
NR4A2 P43354 1/20 0.70
NR4A3 Q92570 1/20 0.70
RAB9A P51151 5/20 0.68
SMN1; SMN2 Q16637 4/20 0.68
MAOB P27338 1/20 0.66
HDAC3 O15379 1/20 0.65
HDAC1 Q13547 1/20 0.65
HDAC2 Q92769 1/20 0.65
NCOR2 Q9Y618 1/20 0.65
SRD5A2 P31213 1/20 0.64
CASP3 P42574 1/20 0.63
TAAR1 Q96RJ0 1/20 0.63
SENP7 Q9BQF6 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28761131 0.86 ALDH1A1 (0.66) ALDH1A1MAPTHTTMAPK1NPC1
SCHEMBL5971699 0.85 NR4A1 (0.68) ALDH1A1MAPTMAPK1NPC1PARP10
SCHEMBL16015339 0.85 MEN1 (0.71) ALDH1A1MAPTHTTMAPK1NPC1
SCHEMBL31148956 0.85 ALDH1A1 (0.69) ALDH1A1MAPTHTTMAPK1NPC1
SCHEMBL1056460 0.85 MRGPRX4 (0.74) ALDH1A1MAPTNPC1PARP10NR4A1
SCHEMBL28255418 0.85 NR4A1 (0.68) ALDH1A1MAPTNPC1PARP10NR4A1
SCHEMBL14924487 0.84 MAPT (1.00) ALDH1A1MAPTHTTMAPK1NPC1
SCHEMBL22192264 0.84 RAB9A (0.94) MAPTNPC1NR4A1NR4A2NR4A3
SCHEMBL28593279 0.84 MAPT (0.73) ALDH1A1MAPTHTTMAPK1NPC1
SCHEMBL28597324 0.84 MEN1 (0.65) ALDH1A1MAPTHTTMAPK1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080895-A Polyglycolic acid composition and preparation method thereof, biodegradable polyester material and application thereof, and PGA temporary plugging ball and preparation method thereof 2026-05-26 CN claimed
WO-2025020685-A1 PEROVSKITE THIN FILM LAYER AND PREPARATION METHOD THEREFOR, AND PEROVSKITE SILICON STACKED SOLAR CELL AND PREPARATION METHOD THEREFOR 通威太阳能(成都)有限公司 2025-01-30 WO claimed
CN-116887609-A Perovskite thin film layer and preparation method thereof, perovskite silicon laminated solar cell and preparation method thereof 通威太阳能(成都)有限公司 2023-10-13 CN claimed
CN-107236106-A The aromatic series terminal hydroxy group chain extender of the key containing acylhydrazone, selfreparing polyurethane and preparation method thereof 青岛科技大学 2017-10-10 CN claimed
EP-0502110-B1 (HETERO) 4-ARYLMETHOXY PHENYL DIAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, AND THEIR THERAPEUTICAL APPLICATIONS SYNTHELABO (FR) 1995-02-01 EP claimed
WO-2025020685-A1 PEROVSKITE THIN FILM LAYER AND PREPARATION METHOD THEREFOR, AND PEROVSKITE SILICON STACKED SOLAR CELL AND PREPARATION METHOD THEREFOR 通威太阳能(成都)有限公司 2025-01-30 WO disclosed
CN-113166114-B Cyclic tetramer compounds as inhibitors of proprotein convertase subtilisin/KEXIN type 9 (PCSK 9) for the treatment of metabolic disorders 诺华股份有限公司 2025-01-03 CN disclosed
CN-118307534-A LTA4H inhibitors and uses thereof 上海海雁医药科技有限公司 2024-07-09 CN disclosed
CN-116730941-B 5-Phenyl-1, 3, 4-oxadiazole compound and preparation method and application thereof 广东省科学院微生物研究所(广东省微生物分析检测中心) 2024-07-02 CN disclosed
US-11813306-B2 Cyclic tetramer compounds as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors for the treatment of metabolic disorders NOVARTIS AG (CH) 2023-11-14 US disclosed
US-11813306-B2 Cyclic tetramer compounds as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors for the treatment of metabolic disorders NOVARTIS AG (CH) 2023-11-14 US disclosed
US-11813306-B2 Cyclic tetramer compounds as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors for the treatment of metabolic disorders NOVARTIS AG (CH) 2023-11-14 US disclosed
US-6069153-A HORMONE REPLACEMENT THERPAY AMERICAN HOME PRODUCTS CORPORATION (US) 2000-05-30 US disclosed
WO-1999058524-A1 BENZOCARBAZOLE AND INDENOINDOLE DERIVED ESTROGENIC AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1999-11-18 WO disclosed
EP-0562824-B1 Thermal recording material FUJI PHOTO FILM CO LTD (JP) 1997-06-11 EP disclosed
US-5464804-A Heat sensitive color layer with electron donor, colorless dye is black color aminofluoran, amino compound and isocyanate compound FUJI PHOTO FILM CO., LTD. (JP) 1995-11-07 US disclosed
US-5288688-A Comprising electron-donating colorless dye, isocyanate and amino compounds; antifogging, discoloration inhibition, storage stability FUJI PHOTO FILM CO., LTD. (JP) 1994-02-22 US disclosed
US-5250551-A Monoamine oxidase inhibitors DELALANDE S.A. (FR) 1993-10-05 US disclosed
EP-0562824-A2 Thermal recording material FUJI PHOTO FILM CO., LTD. (JP) 1993-09-29 EP disclosed
US-5100910-A Monoamine Oxidase Inhibitors DELALANDE S.A. (FR) 1992-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11813306-B2 Cyclic tetramer compounds as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors for the treatment of metabolic disorders PCSK9, PCSK7, PCSK6 ALDH1A1 4739/4885MAPT 114/4885HTT 548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.