Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 9/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | DNMT3B | Q9UBC3 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198512 | 0.87 | DNMT1 (0.63) | DNMT1ADRB1DNMT3BLMNATP53 | |
| SCHEMBL5982343 | 0.87 | DNMT1 (0.63) | DNMT1ADRB1DNMT3BLMNATP53 | |
| SCHEMBL12731448 | 0.87 | DNMT1 (0.63) | DNMT1ADRB1DNMT3BLMNATP53 | |
| SCHEMBL5982335 | 0.87 | DNMT1 (0.63) | DNMT1ADRB1DNMT3BLMNATP53 | |
| SCHEMBL197813 | 0.87 | DNMT1 (0.63) | DNMT1ADRB1DNMT3BLMNATP53 | |
| SCHEMBL8638774 | 0.86 | DNMT1 (0.50) | DNMT1ADRB1ALBDNMT3BLMNA | |
| SCHEMBL3246049 | 0.86 | ALB (0.60) | DNMT1ADRB1ALBDNMT3BLMNA | |
| SCHEMBL20718843 | 0.86 | ALB (0.60) | DNMT1ADRB1ALBDNMT3BLMNA | |
| SCHEMBL9856645 | 0.86 | DNMT1 (0.47) | DNMT1ADRB1ALBDNMT3BLMNA | |
| SCHEMBL8642312 | 0.86 | DNMT1 (0.50) | DNMT1ADRB1ALBDNMT3BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814639-A | TREATING AIDS | EMORY UNIVERSITY (US) | 1998-09-29 | — | — | US | disclosed |
| US-5700937-A | LIPOSOME SUSPENSION FOR TREATMENT OF AIDS | EMORY UNIVERSITY (US) | 1997-12-23 | — | — | US | disclosed |
| US-5210085-A | Treating HIV infections | EMORY UNIVERSITY (US) | 1993-05-11 | — | — | US | disclosed |