Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 9/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | DNMT3B | Q9UBC3 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856650 | 1.00 | DNMT1 (0.47) | DNMT1ADRB1ALBDNMT3BLMNA | |
| SCHEMBL198512 | 0.87 | DNMT1 (0.63) | DNMT1ADRB1DNMT3BLMNATP53 | |
| SCHEMBL197813 | 0.87 | DNMT1 (0.63) | DNMT1ADRB1DNMT3BLMNATP53 | |
| SCHEMBL12731448 | 0.87 | DNMT1 (0.63) | DNMT1ADRB1DNMT3BLMNATP53 | |
| SCHEMBL5982335 | 0.87 | DNMT1 (0.63) | DNMT1ADRB1DNMT3BLMNATP53 | |
| SCHEMBL5982343 | 0.87 | DNMT1 (0.63) | DNMT1ADRB1DNMT3BLMNATP53 | |
| SCHEMBL8639294 | 0.86 | DNMT1 (0.50) | DNMT1ADRB1ALBDNMT3BLMNA | |
| SCHEMBL445990 | 0.86 | DNMT1 (0.47) | DNMT1ADRB1ALBDNMT3BLMNA | |
| SCHEMBL445989 | 0.86 | DNMT1 (0.47) | DNMT1ADRB1ALBDNMT3BLMNA | |
| SCHEMBL13700625 | 0.86 | DNMT1 (0.47) | DNMT1ADRB1ALBDNMT3BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409227-A2 | Pyrimidine nucleosides, their preparation and pharmaceutical preparations | MATTHES, Eckart, Dr. (DE) | 1991-01-23 | — | — | EP | disclosed |