SCHEMBL198512

SCHEMBL198512

Nc1nc(=O)n([C@H]2CC(O)[C@@H](CO)O2)cc1Br

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 6/20 0.63
ADRB1 P08588 1/20 0.63
DNMT3B Q9UBC3 2/20 0.54
LMNA P02545 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
PNP P00491 1/20 0.49
TP53 P04637 1/20 0.49
HTT P42858 1/20 0.49
PDE4D Q08499 1/20 0.49
PDE3A Q14432 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
PIM1 P11309 1/20 0.48
CSNK2A2 P19784 1/20 0.48
CSNK2B P67870 1/20 0.48
CSNK2A1 P68400 1/20 0.48
CSNK2A3 Q8NEV1 1/20 0.48
TK1 P04183 1/20 0.48
FPR2 P25090 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5982343 1.00 DNMT1 (0.63) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL5982335 1.00 DNMT1 (0.63) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL12731448 1.00 DNMT1 (0.63) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL197813 1.00 DNMT1 (0.63) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
Phosphoric Acid SCHEMBL416601 0.95 DNMT1 (0.58) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL9780830 0.91 DNMT1 (0.52) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL9780823 0.91 DNMT1 (0.52) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL5983760 0.88 DNMT1 (0.66) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL5983766 0.88 DNMT1 (0.66) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL9856645 0.87 DNMT1 (0.47) DNMT1ADRB1DNMT3BLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1867 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES, INC. (US) 2025-08-21 US claimed
EP-4271389-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA Rejuvenation Technologies Inc. (US) 2023-11-08 EP claimed
CN-115998630-B Hair-blacking essence and preparation method thereof 北京普世安生物科技有限公司 2023-06-06 CN claimed
CN-115998630-A Hair-blacking essence and preparation method thereof 北京普世安生物科技有限公司 2023-04-25 CN claimed
WO-2022147039-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES INC. (US) 2022-07-07 WO claimed
US-20220096649-A1 IMMUNOMODULATING POLYNUCLEOTIDE CONJUGATES AND METHODS OF USE HORIZON TECHNOLOGY FINANCE CORPORATION 2022-03-31 US claimed
US-11203611-B2 Immunomodulating polynucleotides, antibody conjugates thereof, and methods of their use TOLLNINE, INC. (US) 2021-12-21 US claimed
WO-2020081744-A1 IMMUNOMODULATING POLYNUCLEOTIDE CONJUGATES AND METHODS OF USE TOLLNINE, INC. (US) 2020-04-23 WO claimed
EP-3610022-A1 IMMUNOMODULATING POLYNUCLEOTIDES, ANTIBODY CONJUGATES THEREOF, AND METHODS OF THEIR USE Tollnine, Inc. (US) 2020-02-19 EP claimed
WO-2018189382-A1 IMMUNOMODULATING POLYNUCLEOTIDES, ANTIBODY CONJUGATES THEREOF, AND METHODS OF THEIR USE SOLSTICE BIOLOGICS, LTD. (IE) 2018-10-18 WO claimed
EP-3186387-A1 METHOD OF DETERMINING THE ACTIVITY OF ENZYMES CONVERTING CYTOSINE DERIVATIVES TO URACIL DERIVATIVES IN CELLS, TISSUES AND ORGANISMS Univerzita Palackého v Olomouci (CZ) 2017-07-05 EP claimed
WO-2016029889-A1 METHOD OF DETERMINING THE ACTIVITY OF ENZYMES CONVERTING CYTOSINE DERIVATIVES TO URACIL DERIVATIVES IN CELLS, TISSUES AND ORGANISMS UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2016-03-03 WO claimed
US-20130171635-A1 DUAL OLIGONUCLEOTIDE METHOD OF NUCLEIC ACID DETECTION 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-07-04 US claimed
US-20090325897-A1 DESIGNER THERAPY OF PANCREATIC TUMORS UNIVERSITY OF MIAMI (US) 2009-12-31 US claimed
WO-2008085611-A2 DESIGNER THERAPHY OF PANCREATIC TUMORS UNIVERSITY OF MIAMI (US) 2008-07-17 WO claimed
US-6890736-B1 Methods for producing proteins in cultured cells IMMUNEX CORPORATION (US) 2005-05-10 US claimed
US-6107030-A Determining orientation and direction of DNA sequences THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-08-22 US claimed
EP-4746905-A1 RSV VACCINE Astrazeneca AB (SE) 2026-05-27 EP disclosed
WO-1985001871-A1 METHOD AND MATERIALS FOR SENSITIZING NEOPLASTIC TISSUE TO RADIATION GREER SHELDON B 1985-05-09 WO disclosed
US-4210638-A 5-TRIFLUOROMETHYL-2'-DEOXYCYCTIDINE AND TETRAHYDROURIDINE OR 2'-DEOXYTETRAHYDROURIDINE PCR, INC. (US) 1980-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA RNASE1, POLRMT, TERT DNMT1 384/4885ADRB1 4067/4885DNMT3B 303/4885
US-11203611-B2 Immunomodulating polynucleotides, antibody conjugates thereof, and methods of their use TYMP, DUT, PAICS DNMT1 197/4885ADRB1 4437/4885DNMT3B 512/4885
US-20220096649-A1 IMMUNOMODULATING POLYNUCLEOTIDE CONJUGATES AND METHODS OF USE PBK, CD47, NCL DNMT1 314/4885ADRB1 4293/4885DNMT3B 1100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.